DISEASES

Disease-gene associations mined from literature

Literature associating MARCH11 and autosomal dominant non-syndromic intellectual disability 44

MARCH11 [ENSP00000333181]

Membrane-associated RING finger protein 11; E3 ubiquitin-protein ligase that mediates polyubiquitination of CD4. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates. May play a role in ubuquitin-dependent protein sorting in developmenting spermatids; Membrane associated ring-CH-type fingers

Synonyms:  MARCH11,  MARCH11p,  hMARCH11,  A6NNE9,  A6NNE9p ...

Linkouts:  STRING  Pharos  UniProt  OMIM