Disease-gene associations mined from literature

Literature associating ALDH1A3 and coloboma

ALDH1A3 [ENSP00000332256]

Aldehyde dehydrogenase 1 family, member A3; NAD-dependent aldehyde dehydrogenase that catalyzes the formation of retinoic acid. Has high activity with all-trans retinal, and has much lower in vitro activity with acetaldehyde. Required for the biosynthesis of normal levels of retinoic acid in the embryonic ocular and nasal regions; retinoic acid is required for normal embryonic development of the eye and the nasal region (By similarity).

Synonyms:  ALDH1A3,  ALDH1A3p,  hALDH1A3,  A0A024RC95,  DKFZP686G1675 ...

Linkouts:  STRING  Pharos  UniProt  OMIM