Disease-gene associations mined from literature

Literature associating CD86 and lymphohistiocytoid mesothelioma

CD86 [ENSP00000332049]

T-lymphocyte activation antigen CD86; Receptor involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or CTLA-4. May play a critical role in the early events of T-cell activation and costimulation of naive T-cells, such as deciding between immunity and anergy that is made by T- cells within 24 hours after activation. Isoform 2 interferes with the formation of CD86 clusters, and thus acts as a negative regulator of T-cell activation.

Synonyms:  CD86,  CD86p,  hCD86,  C9JXS1,  P42081 ...

Linkouts:  STRING  Pharos  UniProt  OMIM