Disease-gene associations mined from literature

Literature associating GDF3 and embryonal carcinoma

GDF3 [ENSP00000331745]

Growth differentiation factor 3; Growth factor involved in early embryonic development and adipose-tissue homeostasis. During embryogenesis controls formation of anterior visceral endoderm and mesoderm and the establishment of anterior-posterior identity through a receptor complex comprising the receptor ACVR1B and the coreceptor TDGF1/Cripto (By similarity). Regulates adipose-tissue homeostasis and energy balance under nutrient overload in part by signaling through the receptor complex based on ACVR1C and TDGF1/Cripto; Belongs to the TGF-beta family.

Synonyms:  GDF3,  GDF3p,  hGDF3,  Q9NR23,  Q9NR23p ...

Linkouts:  STRING  Pharos  UniProt  OMIM