Literature associating P2RX7 and cystic kidney disease
Purinergic receptor P2X, ligand-gated ion channel, 7; Receptor for ATP that acts as a ligand-gated ion channel. Responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Could function in both fast synaptic transmission and the ATP-mediated lysis of antigen-presenting cells. In the absence of its natural ligand, ATP, functions as a scavenger receptor in the recognition and engulfment of apoptotic cells; Purinergic receptors P2X
Synonyms: P2RX7, P2RX7p, hP2RX7, B3KR29, F5H237 ...