Disease-gene associations mined from literature

Literature associating GRPEL2 and freemartinism

GRPEL2 [ENSP00000329558]

GrpE protein homolog 2, mitochondrial; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Seems to control the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins. Stimulates ATPase activity of mt-HSP70. May also serve to modulate the interconversion of oligomeric (inactive) and monomeric (active) forms of mt-HSP70 (By similarity); Belongs to the GrpE family.

Synonyms:  GRPEL2,  GRPEL2p,  hGRPEL2,  B4DFA6,  D6RGI6 ...

Linkouts:  STRING  Pharos  UniProt