Literature associating DENND5A and lissencephaly 8
DENN domain-containing protein 5A; Guanine nucleotide exchange factor (GEF) which may activate RAB6A and RAB39A and/or RAB39B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form. Involved in the negative regulation of neurite outgrowth (By similarity); Belongs to the RAB6IP1 family.
Synonyms: DENND5A, DENND5Ap, hDENND5A, B3KWN5, B4DFB6 ...