Literature associating RNF135 and Sotos syndrome
RNF135 [ENSP00000328340]
RING-type E3 ubiquitin transferase RNF135; Acts as an E2-dependent E3 ubiquitin-protein ligase, involved in innate immune defense against viruses. Ubiquitinates DDX58 and is required for full activation of the DDX58 signaling resulting in interferon beta production; Ring finger proteins
Synonyms: RNF135, RNF135p, hRNF135, B3KV69, H7C3H8 ...