DISEASES

Disease-gene associations mined from literature

Literature associating NOG and spina bifida

NOG [ENSP00000328181]

Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. Essential for cartilage morphogenesis and joint formation. Inhibits chondrocyte differentiation through its interaction with GDF5 and, probably, GDF6.

Synonyms:  NOG,  Q13253,  Q13253p,  hQ13253,  1M4U ...

Linkouts:  STRING  Pharos  UniProt  OMIM