Literature associating TNFAIP8L3 and astigmatism
Tumor necrosis factor alpha-induced protein 8-like protein 3; Acts as a lipid transfer protein. Preferentially captures and shuttles two lipid second messengers, i.e., phosphatidylinositol 4,5- bisphosphate and phosphatidylinositol 3,4,5-trisphosphate and increases their levels in the plasma membrane. Additionally, may also function as a lipid-presenting protein to enhance the activity of the PI3K-AKT and MEK-ERK pathways. May act as a regulator of tumorigenesis through its activation of phospholipid signaling; Belongs to the TNFAIP8 family.
Synonyms: TNFAIP8L3, Q5GJ75, Q5GJ75p, hQ5GJ75, TIPE3 ...