DISEASES

Disease-gene associations mined from literature

Literature associating MYT1 and periventricular leukomalacia

MYT1 [ENSP00000327465]

Proteolipid protein-binding protein; Binds to the promoter region of genes encoding proteolipid proteins of the central nervous system. May play a role in the development of neurons and oligodendroglia in the CNS. May regulate a critical transition point in oligodendrocyte lineage development by modulating oligodendrocyte progenitor proliferation relative to terminal differentiation and up- regulation of myelin gene transcription; Belongs to the MYT1 family.

Synonyms:  MYT1,  MYT1p,  hMYT1,  Q01538,  KIAA0835 ...

Linkouts:  STRING  Pharos  UniProt  OMIM