Literature associating ATP13A2 and hereditary spastic paraplegia 35
ATP13A2 [ENSP00000327214]
Cation-transporting ATPase 13A2; ATPase that plays a role in intracellular cation homeostasis and the maintenance of neuronal integrity . Required for a proper lysosomal and mitochondrial maintenance (PubMed:22296644, PubMed:28137957). Regulates the autophagy-lysosome pathway through the control of SYT11 expression at both transcriptional and post- translational levels . ECO:0000269|PubMed:22296644, ECO:0000269|PubMed:27278822,; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.
Synonyms: ATP13A2, ATP13A2p, hATP13A2, A0A087WUM9, H0Y8I1 ...