DISEASES

Disease-gene associations mined from literature

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Literature associating KLK4 and renovascular hypertension

KLK4 [ENSP00000326159]

Enamel matrix serine proteinase 1; Has a major role in enamel formation. Required during the maturation stage of tooth development for clearance of enamel proteins and normal structural patterning of the crystalline matrix (By similarity); Kallikreins

Synonyms:  KLK4,  KLK4p,  hKLK4,  M0QYN5,  Q4VB18 ...

Linkouts:  STRING  Pharos  UniProt  OMIM

The disease-gene associations are derived from automatic text mining of the biomedical literature, manually curated database annotations, cancer mutation data, and genome-wide association studies. The confidence of each association is signified by stars, where ★★★★★ is the highest confidence and ★☆☆☆☆ is the lowest.

Developed by Sune Frankild, Alexander Junge, Albert Pallejà, Dhouha Grissa, Kalliopi Tsafou, and Lars Juhl Jensen from the Novo Nordisk Foundation Center for Protein Research.