DISEASES

Disease-gene associations mined from literature

Literature associating SRSF7 and cataract 34 multiple types

SRSF7 [ENSP00000325905]

Splicing factor, arginine/serine-rich 7; Required for pre-mRNA splicing. Can also modulate alternative splicing in vitro. Represses the splicing of MAPT/Tau exon 10. May function as export adapter involved in mRNA nuclear export such as of histone H2A. Binds mRNA which is thought to be transferred to the NXF1-NXT1 heterodimer for export (TAP/NXF1 pathway); enhances NXF1-NXT1 RNA-binding activity. RNA-binding is semi-sequence specific.

Synonyms:  SRSF7,  SRSF7p,  hSRSF7,  C9JAB2,  F8WEA1 ...

Linkouts:  STRING  Pharos  UniProt  OMIM