DISEASES

Disease-gene associations mined from literature

Literature associating ZNF335 and primary autosomal recessive microcephaly

ZNF335 [ENSP00000325326]

NRC-interacting factor 1; Component or associated component of some histone methyltransferase complexes may regulate transcription through recruitment of those complexes on gene promoters. Enhances ligand- dependent transcriptional activation by nuclear hormone receptors. Plays an important role in neural progenitor cell proliferation and self-renewal through the regulation of specific genes involved brain development, including REST. Also controls the expression of genes involved in somatic development and regulates, for instance, lymphoblast proliferation; Zinc fingers C2H2-type

Synonyms:  ZNF335,  ZNF335p,  hZNF335,  Q9H4Z2,  Q9H4Z2p ...

Linkouts:  STRING  Pharos  UniProt  OMIM