Disease-gene associations mined from literature

Literature associating FLII and bone sarcoma

FLII [ENSP00000324573]

Flightless I homolog (Drosophila); May play a role as coactivator in transcriptional activation by hormone-activated nuclear receptors (NR) and acts in cooperation with NCOA2 and CARM1. Involved in estrogen hormone signaling. Involved in early embryonic development (By similarity). May play a role in regulation of cytoskeletal rearrangements involved in cytokinesis and cell migration, by inhibiting Rac1-dependent paxillin phosphorylation; Gelsolin/villins

Synonyms:  FLII,  J3KS39,  J3KS54,  J3KT47,  J3QLR6 ...

Linkouts:  STRING  Pharos  UniProt  OMIM