Literature associating PENK and withdrawal disorder
Proenkephalin-A; Met- and Leu-enkephalins compete with and mimic the effects of opiate drugs. They play a role in a number of physiologic functions, including pain perception and responses to stress. PENK(114-133) and PENK(237-258) increase glutamate release in the striatum. PENK(114-133) decreases GABA concentration in the striatum; Belongs to the opioid neuropeptide precursor family.
Synonyms: PENK, A0A024R7V4, E5RFR1, E5RIP6, E5RJ72 ...