DISEASES

Disease-gene associations mined from literature

Literature associating UCP3 and obesity

UCP3 [ENSP00000323740]

Uncoupling protein 3 (mitochondrial, proton carrier); UCP are mitochondrial transporter proteins that create proton leaks across the inner mitochondrial membrane, thus uncoupling oxidative phosphorylation. As a result, energy is dissipated in the form of heat. May play a role in the modulation of tissue respiratory control. Participates in thermogenesis and energy balance; Belongs to the mitochondrial carrier (TC 2.A.29) family.

Synonyms:  UCP3,  UCP3p,  hUCP3,  F5H3N5,  P55916 ...

Linkouts:  STRING  Pharos  UniProt  OMIM