Literature associating MMP1 and osteoarthritis
Matrix metallopeptidase 1 (interstitial collagenase); Cleaves collagens of types I, II, and III at one site in the helical domain. Also cleaves collagens of types VII and X. In case of HIV infection, interacts and cleaves the secreted viral Tat protein, leading to a decrease in neuronal Tat's mediated neurotoxicity; Endogenous ligands
Synonyms: MMP1, MMP1p, hMMP1, A5GZ69, B4DN15 ...