Disease-gene associations mined from literature

Literature associating RHBDF2 and nonepidermolytic palmoplantar keratoderma

RHBDF2 [ENSP00000322775]

Rhomboid 5 homolog 2 (Drosophila); Rhomboid protease-like protein which has no protease activity but regulates the secretion of several ligands of the epidermal growth factor receptor. Indirectly activates the epidermal growth factor receptor signaling pathway and may thereby regulate sleep, cell survival, proliferation and migration (By similarity); Belongs to the peptidase S54 family.

Synonyms:  RHBDF2,  RHBDF2p,  hRHBDF2,  K7EIY3,  K7EJ10 ...

Linkouts:  STRING  Pharos  UniProt  OMIM