Disease-gene associations mined from literature

Literature associating SCN4B and Jervell-Lange Nielsen syndrome

SCN4B [ENSP00000322460]

Sodium channel, voltage-gated, type IV, beta subunit; Modulates channel gating kinetics. Causes negative shifts in the voltage dependence of activation of certain alpha sodium channels, but does not affect the voltage dependence of inactivation. Modulates the suceptibility of the sodium channel to inhibition by toxic peptides from spider, scorpion, wasp and sea anemone venom; Sodium voltage-gated channel beta subunits

Synonyms:  SCN4B,  SCN4Bp,  hSCN4B,  B0YJ93,  Q8IWT1 ...

Linkouts:  STRING  Pharos  UniProt  OMIM