DISEASES

Disease-gene associations mined from literature

Literature associating STXBP5 and tongue squamous cell carcinoma

STXBP5 [ENSP00000321826]

Lethal(2) giant larvae protein homolog 3; Plays a regulatory role in calcium-dependent exocytosis and neurotransmitter release. Inhibits membrane fusion between transport vesicles and the plasma membrane. May modulate the assembly of trans-SNARE complexes between transport vesicles and the plasma membrane. Inhibits translocation of GLUT4 from intracellular vesicles to the plasma membrane. Competes with STXBP1 for STX1 binding (By similarity); Belongs to the WD repeat L(2)GL family.

Synonyms:  STXBP5,  STXBP5p,  hSTXBP5,  H7BXC4,  NBLA04300 ...

Linkouts:  STRING  Pharos  UniProt  OMIM