DISEASES

Disease-gene associations mined from literature

Literature associating IL17RA and chronic mucocutaneous candidiasis

IL17RA [ENSP00000320936]

Interleukin 17 receptor A; Receptor for IL17A. Receptor for IL17F. Binds to IL17A with higher affinity than to IL17F. Binds IL17A and IL17F homodimers as part of a heterodimeric complex with IL17RC. Also binds heterodimers formed by IL17A and IL17F as part of a heterodimeric complex with IL17RC. Receptor for IL17C as part of a heterodimeric complex with IL17RE. Activation of IL17RA leads to induction of expression of inflammatory chemokines and cytokines such as CXCL1, CXCL8/IL8 and IL6; CD molecules

Synonyms:  IL17RA,  IL17RAp,  hIL17RA,  F1JZ08,  Q96F46 ...

Linkouts:  STRING  Pharos  UniProt  OMIM