DISEASES

Disease-gene associations mined from literature

Literature associating LYPLA1 and triple-receptor negative breast cancer

LYPLA1 [ENSP00000320043]

Acyl-protein thioesterase 1; Hydrolyzes fatty acids from S-acylated cysteine residues in proteins such as trimeric G alpha proteins or HRAS. Has depalmitoylating activity toward KCNMA1. Has low lysophospholipase activity; Belongs to the AB hydrolase superfamily. AB hydrolase 2 family.

Synonyms:  LYPLA1,  LYPLA1p,  hLYPLA1,  B4DJV9,  B4DP64 ...

Linkouts:  STRING  Pharos  UniProt  OMIM