DISEASES

Disease-gene associations mined from literature

Literature associating PRSS8 and chromophobe renal cell carcinoma

PRSS8 [ENSP00000319730]

Channel-activating protease 1; Possesses a trypsin-like cleavage specificity with a preference for poly-basic substrates. Stimulates epithelial sodium channel (ENaC) activity through activating cleavage of the gamma subunits (SCNN1G); Serine proteases

Synonyms:  PRSS8,  PRSS8p,  hPRSS8,  B4DWP2,  H3BUJ8 ...

Linkouts:  STRING  Pharos  UniProt  OMIM