Literature associating SKA3 and uterine adnexa cancer
SKA3 [ENSP00000319417]
Spindle and kinetochore-associated protein 3; Component of the SKA1 complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation (PubMed:19289083, PubMed:19360002, PubMed:23085020). The SKA1 complex is a direct component of the kinetochore-microtubule interface and directly associates with microtubules as oligomeric assemblies (PubMed:19289083, PubMed:19360002). The complex facilitates the processive movement of microspheres along a microtubule in a depolymerization-coupled manner . In the complex, it mediates the microtubule- stimulated oligomerization . Affinity for microtubules is synergistically enhanced in the presence of the ndc-80 complex and may allow the ndc-80 complex to track depolymerizing microtubules ; Belongs to the SKA3 family.
Synonyms: SKA3, SKA3p, hSKA3, F5GWG1, F5H8H7 ...