Literature associating CYBRD1 and iron metabolism disease
Ferric-chelate reductase 3; Ferric-chelate reductase that reduces Fe(3+) to Fe(2+). Present at the brush border of duodenal enterocytes where it probably reduces dietary Fe(3+) thereby facilitating its transport into the mucosal cells. Uses ascorbate as electron donor. May be involved in extracellular ascorbate recycling in erythrocyte membranes. May also act as a ferrireductase in airway epithelial cells; Cytochrome b561
Synonyms: CYBRD1, CYBRD1p, hCYBRD1, C9JML1, CYBRD1-001 ...