DISEASES

Disease-gene associations mined from literature

Literature associating RAP2B and dilated cardiomyopathy 1P

RAP2B [ENSP00000319096]

RAP2B, member of RAS oncogene family; Small GTP-binding protein which cycles between a GDP- bound inactive and a GTP-bound active form. Involved in EGFR and CHRM3 signaling pathways through stimulation of PLCE1. May play a role in cytoskeletal rearrangements and regulate cell spreading through activation of the effector TNIK. May regulate membrane vesiculation in red blood cells; RAS type GTPase family

Synonyms:  RAP2B,  RAP2Bp,  hRAP2B,  DKFZP547A0616,  P61225 ...

Linkouts:  STRING  Pharos  UniProt  OMIM