Literature associating GEN1 and external ear disease
GEN1 [ENSP00000318977]
GEN1 Holliday junction 5' flap endonuclease; Endonuclease which resolves Holliday junctions by the introduction of symmetrically related cuts across the junction point, to produce nicked duplex products in which the nicks can be readily ligated. Four-way DNA intermediates, also known as Holliday junctions, are formed during homologous recombination and DNA repair, and their resolution is necessary for proper chromosome segregation.
Synonyms: GEN1, GEN1p, hGEN1, E9PLG0, E9PM30 ...