DISEASES

Disease-gene associations mined from literature

Literature associating PINX1 and thrombophlebitis migrans

PINX1 [ENSP00000318966]

PIN2/TERF1 interacting, telomerase inhibitor 1; Microtubule-binding protein essential for faithful chromosome segregation. Mediates TRF1 and TERT accumulation in nucleolus and enhances TRF1 binding to telomeres. Inhibits telomerase activity. May inhibit cell proliferation and act as tumor suppressor; Belongs to the PINX1 family.

Synonyms:  PINX1,  PINX1p,  hPINX1,  E5RGR1,  E5RJG9 ...

Linkouts:  STRING  Pharos  UniProt