DISEASES

Disease-gene associations mined from literature

Literature associating TRAF7 and transitional meningioma

TRAF7 [ENSP00000318944]

TNF receptor-associated factor 7, E3 ubiquitin protein ligase; E3 ubiquitin ligase capable of auto-ubiquitination, following phosphorylation by MAP3K3. Potentiates MEKK3-mediated activation of the NF-kappa-B, JUN/AP1 and DDIT3 transcriptional regulators. Induces apoptosis when overexpressed; Belongs to the WD repeat TRAF7 family.

Synonyms:  TRAF7,  TRAF7p,  hTRAF7,  D3DU86,  H3BR17 ...

Linkouts:  STRING  Pharos  UniProt  OMIM