Literature associating GREM2 and tooth agenesis
Cysteine knot superfamily 1, BMP antagonist 2; Cytokine that inhibits the activity of BMP2 and BMP4 in a dose-dependent manner, and thereby modulates signaling by BMP family members. Contributes to the regulation of embryonic morphogenesis via BMP family members. Antagonizes BMP4-induced suppression of progesterone production in granulosa cells.
Synonyms: GREM2, GREM2p, hGREM2, A0A024R3Y1, Q9H772 ...