Literature associating DUOX1 and autosomal recessive chronic granulomatous disease cytochrome b-negative
NADPH thyroid oxidase 1; Generates hydrogen peroxide which is required for the activity of thyroid peroxidase/TPO and lactoperoxidase/LPO. Plays a role in thyroid hormones synthesis and lactoperoxidase-mediated antimicrobial defense at the surface of mucosa. May have its own peroxidase activity through its N-terminal peroxidase-like domain; EF-hand domain containing
Synonyms: DUOX1, DUOX1p, hDUOX1, H0YK19, H0YNR5 ...