DISEASES

Disease-gene associations mined from literature

Literature associating LPCAT4 and endometriosis of ovary

LPCAT4 [ENSP00000317300]

1-alkenylglycerophosphoethanolamine O-acyltransferase; Displays acyl-CoA-dependent lysophospholipid acyltransferase activity with a subset of lysophospholipids as substrates; converts lysophosphatidylethanolamine to phosphatidylethanolamine, lysophosphatidylcholine to phosphatidycholine, 1-alkenyl-lysophatidylethanolamine to 1- alkenyl-phosphatidylethanolamine, lysophosphatidylglycerol and alkyl-lysophosphatidylcholine to phosphatidylglycerol and alkyl- phosphatidylcholine, respectively. In contrast, has no lysophosphatidylinositol, glycerol-3-phosphate, diacylglycerol or lysophosphatidic acid acyltransferase activity. Prefers long chain acyl-CoAs (C16, C18) as acyl donors; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

Synonyms:  LPCAT4,  LPCAT4p,  hLPCAT4,  B7ZM32,  H3BMK4 ...

Linkouts:  STRING  Pharos  UniProt  OMIM