Literature associating ADCK4 and focal segmental glomerulosclerosis
AarF domain-containing protein kinase 4; Atypical kinase involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration. Its substrate specificity is unclear: does not show any protein kinase activity. Probably acts as a small molecule kinase, possibly a lipid kinase that phosphorylates a prenyl lipid in the ubiquinone biosynthesis pathway. Required for podocyte migration.
Synonyms: ADCK4, ADCK4p, hADCK4, A0A024R0Q9, COQ8B ...