Literature associating WHSC1L1 and Weaver syndrome
WHSC1-like 1 isoform 9 with methyltransferase activity to lysine; Histone methyltransferase. Preferentially methylates 'Lys-4' and 'Lys-27' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation, while 'Lys-27' is a mark for transcriptional repression.
Synonyms: WHSC1L1, WHSC1L1p, hWHSC1L1, E9PKA2, E9PQ95 ...