Disease-gene associations mined from literature

Literature associating SPHK1 and estrogen-receptor positive breast cancer

SPHK1 [ENSP00000313681]

Sphingosine kinase 1; Catalyzes the phosphorylation of sphingosine to form sphingosine 1-phosphate (SPP), a lipid mediator with both intra- and extracellular functions. Also acts on D-erythro- sphingosine and to a lesser extent sphinganine, but not other lipids, such as D,L-threo-dihydrosphingosine, N,N- dimethylsphingosine, diacylglycerol, ceramide, or phosphatidylinositol.

Synonyms:  SPHK1,  SPHK1p,  hSPHK1,  K7EJ32,  K7EMA4 ...

Linkouts:  STRING  Pharos  UniProt  OMIM