DISEASES

Disease-gene associations mined from literature

Literature associating RNASEH1 and ataxia with oculomotor apraxia type 2

RNASEH1 [ENSP00000313350]

Ribonuclease H type II; Endonuclease that specifically degrades the RNA of RNA- DNA hybrids. Plays a role in RNA polymerase II (RNAp II) transcription termination by degrading R-loop RNA-DNA hybrid formation at G-rich pause sites located downstream of the poly(A) site and behind the elongating RNAp II; Belongs to the RNase H family.

Synonyms:  RNASEH1,  RNASEH1p,  hRNASEH1,  B3KUD4,  E5KN15 ...

Linkouts:  STRING  Pharos  UniProt  OMIM