Disease-gene associations mined from literature

Literature associating SNX14 and beta-mannosidosis

SNX14 [ENSP00000313121]

Sorting nexin 14; Plays a role in maintaining normal neuronal excitability and synaptic transmission. May be involved in several stages of intracellular trafficking (By similarity). Required for autophagosome clearance, possibly by mediating the fusion of lysosomes with autophagosomes (Probable). Binds phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2), a key component of late endosomes/lysosomes. Does not bind phosphatidylinositol 3-phosphate (PtdIns(3P)); Sorting nexins

Synonyms:  SNX14,  SNX14p,  hSNX14,  D6RBA7,  D6RDA6 ...

Linkouts:  STRING  Pharos  UniProt