Literature associating DEFB114 and autosomal recessive congenital ichthyosis 1
Defensin, beta 114; Has a salt-sensitive antimicrobial activity against Gram-negative bacteria, including E.coli, Gram-positive, including S.aureus, and fungi, including C.albicans. Binds to and neutralizes bacterial lipopolysaccharides (LPS), abolishing TNF production by macrophages challenged with LPS. Rescues the LPS- induced reduction of sperm motility in vitro and may protect from LPS-induced lethality; Defensins, beta
Synonyms: DEFB114, DEFB114p, hDEFB114, Q30KQ6, DEFB14 ...