Disease-gene associations mined from literature

Literature associating PPARGC1B and kidney lipoma

PPARGC1B [ENSP00000312649]

Peroxisome proliferator-activated receptor gamma, coactivator 1 beta; Plays a role of stimulator of transcription factors and nuclear receptors activities. Activates transcriptional activity of estrogen receptor alpha, nuclear respiratory factor 1 (NRF1) and glucocorticoid receptor in the presence of glucocorticoids. May play a role in constitutive non-adrenergic-mediated mitochondrial biogenesis as suggested by increased basal oxygen consumption and mitochondrial number when overexpressed. May be involved in fat oxidation and non-oxidative glucose metabolism and in the regulation of energy expenditure. Induces the expression of PERM1 in the skeletal muscle in an ESRRA-dependent manner; RNA binding motif containing

Synonyms:  PPARGC1B,  Q86YN6,  PERC,  PGC1,  PGC1B ...

Linkouts:  STRING  Pharos  UniProt  OMIM