Disease-gene associations mined from literature

Literature associating PPM1E and mulibrey nanism

PPM1E [ENSP00000312411]

Ca(2+)/calmodulin-dependent protein kinase phosphatase N; Protein phosphatase that inactivates multifunctional CaM kinases such as CAMK4 and CAMK2 (By similarity). Dephosphorylates and inactivates PAK. May play a role in the inhibition of actin fiber stress breakdown and in morphological changes driven by TNK2/CDC42. Dephosphorylates PRKAA2 (By similarity); Protein phosphatases, Mg2+/Mn2+ dependent

Synonyms:  PPM1E,  PPM1Ep,  hPPM1E,  A7E2X1,  Q8WY54 ...

Linkouts:  STRING  Pharos  UniProt