DISEASES

Disease-gene associations mined from literature

Literature associating PRG2 and Loeffler endocarditis

PRG2 [ENSP00000312134]

Proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein); Cytotoxin and helminthotoxin. Also induces non-cytolytic histamine release from human basophils. Involved in antiparasitic defense mechanisms and immune hypersensitivity reactions. The proform acts as a proteinase inhibitor, reducing the activity of PAPPA; C-type lectin domain containing

Synonyms:  PRG2,  PRG2p,  hPRG2,  A6XMW0,  P13727 ...

Linkouts:  STRING  Pharos  UniProt  OMIM