DISEASES

Disease-gene associations mined from literature

Literature associating TLR8 and toxic pneumonitis

TLR8 [ENSP00000312082]

Toll-like receptor 8; Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response; CD molecules

Synonyms:  TLR8,  TLR8p,  hTLR8,  B4DLJ2,  Q8NC00 ...

Linkouts:  STRING  Pharos  UniProt