DISEASES

Disease-gene associations mined from literature

Literature associating MRGPRD and femoral cancer

MRGPRD [ENSP00000310631]

Mas-related G-protein coupled receptor member D; May regulate nociceptor function and/or development, including the sensation or modulation of pain. Functions as a specific membrane receptor for beta-alanine. Beta-alanine at micromolar doses specifically evoked Ca(2+) influx in cells expressing the receptor. Beta-alanine decreases forskolin- stimulated cAMP production in cells expressing the receptor, suggesting that the receptor couples with G-protein G(q) and G(i); G protein-coupled receptors, Class A orphans

Synonyms:  MRGPRD,  Q8TDS7,  MRGD,  Q8TDS7p,  hQ8TDS7 ...

Linkouts:  STRING  Pharos  UniProt  OMIM