DISEASES

Disease-gene associations mined from literature

Literature associating LPL and cerebrovascular disease

LPL [ENSP00000309757]

Lipoprotein lipase; The primary function of this lipase is the hydrolysis of triglycerides of circulating chylomicrons and very low density lipoproteins (VLDL). Binding to heparin sulfate proteogylcans at the cell surface is vital to the function. The apolipoprotein, APOC2, acts as a coactivator of LPL activity in the presence of lipids on the luminal surface of vascular endothelium (By similarity); Belongs to the AB hydrolase superfamily. Lipase family.

Synonyms:  E5RHN7,  E5RJI0,  E5RJZ4,  E7EW14,  P06858 ...

Linkouts:  STRING  Pharos  UniProt  OMIM