Literature associating GP6 and thrombocytopenia due to platelet alloimmunization
Glycoprotein VI (platelet); Collagen receptor involved in collagen-induced platelet adhesion and activation. Plays a key role in platelet procoagulant activity and subsequent thrombin and fibrin formation. This procoagulant function may contribute to arterial and venous thrombus formation. The signaling pathway involves the FcR gamma- chain, the Src kinases (likely FYN or LYN) and SYK, the adapter protein LAT and leads to the activation of PLCG2; Ig-like cell adhesion molecule family
Synonyms: GP6, GP6p, hGP6, GP6-001, GP6-002 ...