Disease-gene associations mined from literature

Literature associating GP6 and thrombocytopenia due to platelet alloimmunization

GP6 [ENSP00000308782]

Glycoprotein VI (platelet); Collagen receptor involved in collagen-induced platelet adhesion and activation. Plays a key role in platelet procoagulant activity and subsequent thrombin and fibrin formation. This procoagulant function may contribute to arterial and venous thrombus formation. The signaling pathway involves the FcR gamma- chain, the Src kinases (likely FYN or LYN) and SYK, the adapter protein LAT and leads to the activation of PLCG2; Ig-like cell adhesion molecule family

Synonyms:  GP6,  GP6p,  hGP6,  GP6-001,  GP6-002 ...

Linkouts:  STRING  Pharos  UniProt  OMIM