DISEASES

Disease-gene associations mined from literature

Literature associating PRSS1 and cystic fibrosis

PRSS1 [ENSP00000308720]

Protease, serine, 1 (trypsin 1); Has activity against the synthetic substrates Boc-Phe- Ser-Arg-Mec, Boc-Leu-Thr-Arg-Mec, Boc-Gln-Ala-Arg-Mec and Boc-Val- Pro-Arg-Mec. The single-chain form is more active than the two- chain form against all of these substrates; Belongs to the peptidase S1 family.

Synonyms:  PRSS1,  PRSS1p,  hPRSS1,  E7EQ64,  P07477 ...

Linkouts:  STRING  Pharos  UniProt  OMIM