DISEASES

Disease-gene associations mined from literature

Literature associating F2 and hemorrhagic disease

F2 [ENSP00000308541]

Coagulation factor II (thrombin); Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.

Synonyms:  F2p,  hF2,  C9JV37,  E9PIT3,  P00734 ...

Linkouts:  STRING  Pharos  UniProt  OMIM