Disease-gene associations mined from literature

Literature associating LEMD3 and congenital muscular dystrophy due to LMNA mutation

LEMD3 [ENSP00000308369]

Inner nuclear membrane protein Man1; Can function as a specific repressor of TGF-beta, activin, and BMP signaling through its interaction with the R-SMAD proteins. Antagonizes TGF-beta-induced cell proliferation arrest; LEM domain containing

Synonyms:  LEMD3,  LEMD3p,  hLEMD3,  A0A024RBB9,  B4DI45 ...

Linkouts:  STRING  Pharos  UniProt  OMIM